| Catalog No |
: |
IMG-71362 |
| Contents |
: |
0.05 mg of purified antibody at a concentration of 1 mg/ml. Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide |
| Isotype |
: |
Rabbit IgG |
| Clone |
: |
N/A |
| Purification |
: |
Antigen Affinity Chromatography |
| Species |
: |
Human |
| Host |
: |
Rabbit |
|
| Application
IHC (paraffin): 6 ug/ml
Storage
Store at -20°C. For long term storage, store at -70°C
Recommended Positive Control : Human Heart, Vessel |
Background
EDG1, a Lysophospholipid/Lysosphingolipid Receptor, binds sphingosine-1-phosphate and may control cell proliferation, survival, and suppression of apoptosis. Overexpression of EDG-1 leads to increased cell-cell aggregation and overexpression of cadherins. EDG-1 transcripts have been reported to be present in embryonic and adult brain, lung alveolar macrophages, vascular smooth muscle cells, endothelial cells, fibroblasts, melanocytes, and TAg-Jurkat T cells, but to be absent from breast cancer cell lines. ESTs have been isolated from brain, breast, heart, heart/melanocyte/uterus, kidney, liver, liver/spleen, lung, nerve, placenta, prostate, tonsil, uterus, and vessel libraries. |
