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Datasheet
Peptide-affinity Purified Polyclonal Antibody to ATP-Binding Cassette, Sub-Family B (Mdr/Tap), Member 1 (Abcb1)
Cat.No IMG-72080
Description ATP-Binding Cassette, Sub-Family B (Mdr/Tap), Member 1 (Abcb1)
Format Purified, Peptide Affinity
Unit 0.05 mg
Price(USD) 395.00
MSDS
Catalog No
:
IMG-72080
Contents
:
0.05 mg of purified antibody in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide
Isotype
:
Rabbit IgG
Clone
:
N/A
Purification
:
Antigen Affinity Chromatography
Species
:
Human
Host
:
Rabbit
Application
IHC (paraffin): 20 µg/ml Storage Store at -20°C. For long term storage, store at -70°C Recommended Positive Control : Adrenal, Cortex
Background Principal Names: ABC20, ABCB1, CD243, CLCS, EC 3.6.3.44, GP170, MDR1, P-GP, PGY1; The human multidrug resistance gene MDR1 encodes a membrane-bound protein, referred to as P-glycoprotein that acts as a pump to extrude toxins from cells. The 3' untranslated region (3'UTR) of the human MDR1 mRNA is very AU-rich (70%). MDR1 is a member of the super family of ATP-binding cassette (ABC) transporters. MDR1 is a member of the MDR/TAP subfamily. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. It is expressed in human liver, kidney, small intestine and brain. It is localized to human chromosome 7q21.1.
Antigen
Synthetic peptide - KLH conjugated corresponding to cytoplasmic domain of human ATP-Binding Cassette, Sub-Family B (Mdr/Tap), Member 1 (Abcb1)
IHC analysis of Formalin-fixed Paraffin embedded Adrenal, Cortex using IMG-72080 at 20 µg/ml.
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Related Products
Research purposes only.
Not for diagnostic or in vivo use. This product is guaranteed to perform as indicated on the datasheet for one year from the date of purchase.
Related Products
Related Product(s) of the Catalog # IMG-72080
No related products found.
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IMG-72080 [Peptide-affinity Purified Polyclonal Antibody to ATP-Binding Cassette, Sub-Family B (Mdr/Tap), Member 1 (Abcb1)]
