Metformin inhibits TNF-alpha-induced IkappaB kinase phosphorylation, IkappaB-alpha degradation and IL-6 production in endothelial cells through PI3K-dependent AMPK phosphorylation.

TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.

Studies of the Interaction of the Viral Suppressor of RNA Silencing Protein p19 with Small RNAs Using Fluorescence Polarization.

The Efficacy of Generating Three Independent Anti-HIV-1 siRNAs from a Single U6 RNA Pol III-Expressed Long Hairpin RNA.

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

Role of NF-kappaB-dependent induction of cytokines in the regulation of vasopressin V1A-receptors during cecal ligation and puncture-induced circulatory failure.

The DHR1 Domain of DOCK180 Binds to SNX5 and Regulates Cation-independent Mannose 6-phosphate Receptor Transport.

BRCA1 Is Required for Meiotic Spindle Assembly and Spindle Assembly Checkpoint Activation in Mouse Oocytes.

P2X7 receptor-Pannexin1 complex: Pharmacology and signaling.

Autophagosome Supports Coxsackievirus B3 Replication In Host Cells.

Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells.

Novel MMP-9 substrates in cancer cells revealed by a label-free quantitative proteomics approach.

The SHOOT ORGANIZATION2 gene coordinates leaf domain development along the central-marginal axis in rice.

siRNA Directed Against Survivin Enhances Pancreatic Cancer Cell Gemcitabine Chemosensitivity.

Endothelial PKCdelta activation attenuates neutrophil transendothelial migration.

Locally administered lentivirus-mediated siRNA inhibits wear debris-induced inflammation in murine air pouch model.

Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2.

Evidence for the evolutionary nascence of a novel sex determination pathway in honeybees.

Role of STAT3 as a Negative Regulator in Mac2- Binding Protein Expression.

Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1.

CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells.

Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma.

The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation.

Curcumin blocks RON tyrosine kinase-mediated invasion of breast carcinoma cells.

NO signaling confers cytoprotectivity through the survivin network in ovarian carcinomas.

The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kappaB pathway to modulate epithelial cell growth.

Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition.

Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development.

Hsp90{beta} and p130cas: novel regulatory factors of MMP-13 expression in human osteoarthritic chondrocytes.

Snail regulates cell-matrix adhesion by regulation of the expression of integrins and basement membrane proteins.

Novel calcineurin interacting protein-2: the functional characterization of CNP-2 in Caenorhabditis elegans.

Does RNA interference influence meiotic crossing over in Drosophila melanogaster?

NOX4 Regulates ROS Levels under Normoxic and Hypoxic Conditions, Triggers Proliferation, and Inhibits Apoptosis in Pulmonary Artery Adventitial Fibroblasts.

OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics.

AsiDesigner: exon-based siRNA design server considering alternative splicing.

pssRNAMiner: a plant short small RNA regulatory cascade analysis server.

Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.

Frizzled-7 as a potential therapeutic target in colorectal cancer.

Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint.

BCL-X(L) regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.

The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma.

N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma.

Prevention of inflammation-mediated neurotoxicity by rg3 and its role in microglial activation.

Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites.

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection. A New Paradigm for Ischemic Preconditioning.

Cytokine-induced {beta}-cell death is independent of endoplasmic reticulum stress signaling.

HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells.

Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy.

Expression of CYP4A1 in U251 Human Glioma Cell Induces Hyperproliferative Phenotype in vitro and Rapidly Growing Tumors in vivo.

Na+/H+ exchanger is required for hyperglycemia-induced endothelial dysfunction via calcium-dependent calpain.

Activation of protein kinase Calpha signaling prevents cytotoxicity and mutagenicity following lead acetate in CL3 human lung cancer cells.

RNA-silencing in Penicillium chrysogenum and Acremonium chrysogenum: Validation studies using beta-lactam genes expression.

CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP.

Nrf2 regulates curcumin-induced aldose reductase expression indirectly via nuclear factor-kappaB.

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei.

Methylation of the Calcium Channel-Related Gene, CACNA2D3, Is Frequent and a Poor Prognostic Factor in Gastric Cancer.

P-glycoprotein down-regulates expression of breast cancer resistance protein in a drug-free state.

Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer.

HVJ envelope vector, a versatile delivery system: Its development, application, and perspectives.

Suppression of local invasion of ameloblastoma by inhibition of matrix metalloproteinase-2 in vitro.

The role of gamma-synuclein in cocaine-induced behaviour in rats.

Interactions between drebrin and Ras regulate dendritic spine plasticity.

Phospholipase Cdelta1 regulates cell proliferation and cell cycle progression from G1 to S phase by control of cyclin E/CDK2 activity.

New Advances in RNAs.

Improvement of recombinant hGM-CSF production by suppression of cysteine proteinase gene expression using RNA interference in a transgenic rice culture.

Calmodulin modulates Akt activity in human breast cancer cell lines.

Protein kinase CK2 and cell polarity.

Adaptive response to GSH depletion and resistance to L: -buthionine-(S,R)-sulfoximine: involvement of Nrf2 activation.

PMX464, a thiol-reactive quinol and putative thioredoxin inhibitor, inhibits NF-kappaB-dependent proinflammatory activation of alveolar epithelial cells.

In vivo inhibition of focal adhesion kinase causes insulin resistance.

TIMAP IS A POSITIVE REGULATOR OF PULMONARY ENDOTHELIAL BARRIER FUNCTION.

The role of transcriptional activator GATA-1 at human {beta}-globin HS2.

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression.

Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules.

PAK is regulated by PI3K, PIX, Cdc42 and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced P38 pathway.

NF-kappa B inhibits sodium transport via down-regulation of SGK1 in renal collecting duct principal cells.

Molecular cloning and functional characterization of porcine IFN-beta promoter stimulator 1 (IPS-1).

Reduced nitric oxide production and iNOS mRNA expression in IFN-gamma-stimulated chicken macrophages transfected with iNOS siRNAs.

The Tribolium ortholog of knirps and knirps-related is crucial for head segmentation but plays a minor role during abdominal patterning.

Identification of JAK/STAT pathway regulators-Insights from RNAi screens.

Epigallocatechin activates haeme oxygenase-1 expression via protein kinase Cdelta and Nrf2.

Tumor necrosis factor alpha small interfering RNA decreases herpes simplex virus-induced inflammation in a mouse model.

Synaptic adhesion-like molecules (SALMs) promote neurite outgrowth.

Staufen1 is expressed in preimplantation mouse embryos and is required for embryonic stem cell differentiation.

p42/44 MAPK is an essential effector for purine nucleoside-mediated neuroprotection of hypoxic PC12 cells and primary cerebellar granule neurons.

The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions.

Evidence that Cisplatin-induced Auditory Damage is Attenuated by Downregulation of Pro-inflammatory Cytokines Via Nrf2/HO-1.

Inhibition of multi-drug resistance of ovarian carcinoma by small interfering RNA targeting to MRP2 gene.

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response.

Requirement of TLR2-mediated signalling for the induction of IL-15 gene expression in human monocytic cells by HSV-1.

IFATS Series: Selenium Induces Improvement of Stem Cell Behaviors in Human Adipose-Tissue Stromal Cells via SAPK/JNK and Stemness Acting Signals.

Silencing onion lachrymatory factor synthase causes a significant change in the sulfur secondary metabolite profile.

Caffeine stimulates cytochrome oxidase expression and activity in the striatum in a sexually-dimorphic manner.

ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in anti-hormone resistant breast cancer cells.

Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus.

TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages.

Role of Human Aquaporin 5 In Colorectal Carcinogenesis.

Transforming Growth Factor-{beta} Stimulates Intestinal Epithelial Focal Adhesion Kinase Synthesis via Smad- and p38-Dependent Mechanisms.

Epac mediates cyclic AMP-dependent axon growth, guidance and regeneration.

Endothelial cell-derived bone morphogenetic proteins control proliferation of neural stem/progenitor cells.